Privigen® First-time Dosing for Patients With PI and ITP

First-time Dosing—Beginning All Patients at Minimum Infusion Rate

When transitioning patients from one Ig product to another, such as from lyophilized to liquid Ig products, always start at the minimum rate of infusion.

Privigen® offers adaptable dosing and a rapid-rate of infusion for carefully selected patients. Because of the differences between brands of IVIg, please review the full site for additional benefits of Privigen®.

If you’re infusing Privigen® for the first time, read the recommendations below for first-time dosing.

First-time Dosing—PI

For patients with PI, the usual dose of Privigen® is 200–800 mg/kg, administered every 3 to 4 weeks.

The recommended initial infusion rate is 0.5 mg/kg/min (0.005 mL/kg/min). If the infusion is well tolerated, the rate of administration may be gradually increased to 8 mg/kg/min
(0.08 mL/kg/min).

First-time Dosing—ITP

The recommended initial infusion rate is 0.5 mg/kg/min (0.005 mL/kg/min); if well tolerated, the rate may be increased gradually to a rate of 4 mg/kg/min (0.04 mL/kg/min).

First-time Dosing—Beginning All Patients at Minimum Infusion Rate

As with any IVIg therapy, Privigen® should be administered at the minimum infusion rate practicable in patients judged to be at risk of renal dysfunction or thrombotic events. Similarly, patients with pre-existing renal insufficiency should not be volume-depleted when initiating IVIg therapy. The patient’s vital signs should be monitored carefully throughout the infusion.

Please see the Important Safety Information and full Prescribing Information.