Manufactured to maintain quality and safety
Privigen IVIg is made from large amounts of plasma (the liquid part of the blood) donated by carefully selected donors across the US. The Privigen manufacturing process inactivates and removes viruses and other infectious agents, although the risk of transmission cannot be completely removed.
CSL Behring has 100+ years of experience in developing and delivering innovative therapies
CSL Behring has implemented some of the most rigorous quality controls in the business to produce products that meet exacting standards.
The Privigen manufacturing process includes a 3-step virus inactivation/removal process
The manufacturing process of Privigen includes screening plasma donors for prior exposure to certain viruses, testing for the presence of certain current viral infections, and including virus inactivation/removal steps to reduce the risk of transmission of infectious agents; however, the risk of transmission of infectious agents, including viruses, cannot be completely removed.
Ig IsoLo®—an additional manufacturing process to help reinforce Privigen quality
Privigen goes through an additional filtration process called immunoaffinity chromatography (IAC).
IAC removes specific antibodies (anti-A and anti-B) that could otherwise lead to clumping (referred to as isoagglutination), which may be harmful to some people. IAC binds these antibodies and removes them while still retaining therapeutic IgG antibodies.
Privigen is an IVIg solution with reduced isoagglutinin levels due to the IAC process.
Only Privigen IVIg is made stable with proline
Proline is a natural amino acid that is made in your body.
Proline is contained in certain foods found in many people's diets.
After extensive study, proline was carefully chosen to be the stabilizer in Privigen. As a result, Privigen can be stored at room temperature (up to 77°F) and is ready to use right off the shelf. Treatment with Privigen should not occur if your doctor determines that you have too much proline in the blood, also called hyperprolinemia.
Proline also occurs naturally in foods such as:
- Dairy Products
- Meat
- Eggs
Privigen may be an option for people who have latex allergies, sensitivity to preservatives, or those who need to limit their sugar intake
Talk to your doctor to see if Privigen is an appropriate IVIg treatment for you.
Privigen is proven safe & effective
Study ResultsReceiving Privigen therapy
Infusion Process