Privigen IVIg—safety and efficacy you can trust
Clinically proven to improve motor function in adults with CIDP
Privigen provides immunoglobulin G (IgG) antibodies that may help block your immune system from attacking the protective myelin covering of nerves in the arms, legs, hands, and feet. Even so, exactly how Privigen works is not completely understood.
Two clinical studies, named PRIMA and PATH, demonstrated that Privigen is an effective treatment for CIDP
PRIMA was the first clinical trial to evaluate the use of Privigen in 28 adult patients with CIDP. Thirteen patients had previously received IVIg treatment, and 15 patients had not previously received any treatment for their CIDP.
The PATH study was the second clinical trial, and the largest IgG study in CIDP to date, to evaluate the use of Privigen in 207 adults with CIDP who had previously been treated with and were dependant on IVIg.
In both studies, all patients received a Privigen loading dose of 2 g/kg followed by PRIVIGEN maintenance doses of 1 g/kg for up to 21 weeks with a 3 week follow up period.
PRIMA study
61%
of patients responded to Privigen
PATH study
73%
of patients responded to Privigen
Most study participants experienced improvements with Privigen IVIg in:
upper body
strength
grip
strength
lower body
strength
*Response rate was defined as percentage of patients who had at least a 1-point decrease in their INCAT score.
Privigen safety
97%
of side effects were
mild/moderate
In PRIMA and PATH, 97% of the side effects reported were mild or moderate in intensity.
Most common* Privigen side effects in adults with CIDP
- Headache
- Asthenia
- Hypertension
- Nausea
- Pain in extremity
- Hemolysis
- Influenza-like illness
- Leukopenia
- Rash
Two patients in the PRIMA study and 8 patients in PATH had serious side effects. These included hemolysis (breakdown of red blood cells[2]), breakdown of red blood cells (2), exacerbation of CIDP (2), acute rash, increased blood pressure, hypersensitivity, blood clot in the lung, respiratory failure, and migraine.
These are not the only side effects possible; see the full prescribing information, including boxed warning, for a complete list of adverse reactions possible with treatment for each condition.
Call your doctor if you experience any side effects, or if you have any other questions or concerns.
*Occurring in more than 5% of people in the clinical trials.
Would you like to learn about Ig therapy that you can infuse yourself?
Please see Important Safety Information below and full prescribing information for Hizentra, including boxed warning and patient product information.
(Immune Globulin Subcutaneous
[Human] 20% Liquid)
Heritage of safety and
excellence
Receiving Privigen
therapy
The support
you need,
all in one place